COVID-19 vaccine development pipeline gears up

[camberiu]

 

[lunar]

Regarding vaccine efficacy, it's a complex subject. To take the Oxford vaccine as an example, the 60% you refer to is some midpoint between ...

Oxford/Astrazeneca did something strange during their clinical studies. 60% efficacy is recorded when two doses are administered at once. 90% efficacy - when half-dose is administered first, and second dose a month later. And normal approach is one full dose, followed by another one a month later. So, the results are difficult to interpret. I believe the efficacy of Astrazeneca will be revised up when data from UK vaccination will become available.

AstraZeneca: ‘Winning’ vaccine formula is 100% effective against severe COVID-19

Following criticism over initial trial, pharma giant's CEO believes general efficacy will be equal to Pfizer-BioNTech, Moderna; says data will be published 'at some point'

www.timesofisrael.com

 

[gracielle]

La OMS entregará millones de dosis en Latinoamérica a través del sistema COVAX en febrero

Los presidentes de Bolivia, Paraguay, Colombia y Guatemala afirmaron a través de sus redes sociales la llegada de lotes de vacunas a sus respectivos países.

www.perfil.com

01 February 2021
The WHO will deliver millions of doses in Latin America through the COVAX Initiative in February. The presidents of Bolivia, Paraguay, Colombia and Guatemala affirmed through their social networks the arrival of batches of vaccines to their respective countries.

According to the Europa Press news agency, Bolivia began its first vaccination campaign last Friday, January 29, with the administration of the Russian Sputnik V vaccine to health personnel. Meanwhile, Colombia, Paraguay and Guatemala plan to start the administration of the vaccines in the coming months. The president of Colombia, Ivan Duque, assured: "The COVAX Initiative confirmed that Colombia is in the first group of nations that will receive, in February, the vaccines from Pfizer/Biontech and AstraZeneca acquired within this strategy." Along the same lines, the president of Guatemala, Alejandro Guiammattei, indicated that "the first batch of vaccines was assigned to Guatemala, which consists of more than 800,000 doses that will arrive in our country between mid and late February. In Paraguay, 300,000 doses will be delivered, as recognized by the president, Mario Abdo. These four Latin American countries are mired in the second wave of the coronavirus pandemic that the region is experiencing, with several spikes in new cases and record number of deaths.

Cuándo llegarán a la Argentina las vacunas de Covax

El Gobierno estima que a través del sistema van a conseguir 9 millones de dosis. Cómo funciona la lista de prioridades.

www.perfil.com

01 February 2021
When will the Covax vaccines arrive in Argentina? The Government estimates that through the system they will get 9 million doses. How the priority list works....
....In this way, the initiative offers:
*Vaccine doses for at least 20% of the population of the countries.
*A diversified and actively managed injection portfolio .
*Delivery of immunizations as soon as they are available.

COVAX acts as an intermediary, that is, it is in charge of negotiating between companies and governments, and also serves as a collector. Its funds are obtained from what it receives in donations from countries, individuals and entities with a philanthropic profile to subsidize the states with fewer possibilities. Argentina is one of the 190 nations that are within the fund. The government of Alberto Fernandez announced that it has the delivery of 51 million doses until July, according to contracts signed with the Gamaleya Institute of Russia (Sputnik V), Oxford-AstraZeneca and the COVAX Initiative.

Government forecasts of the arrival of vaccines based on signed contracts. (Source: Chequeado)

....Following a series of deals secured by Gavi, the vaccines developed by AstraZeneca and Pfizer-BioNTech should be the first to ship in February, with others to join by April 2021, including Novavax and Johnson & Johnson.

Vaccine supplies are expected to increase steadily month-over-month this year. Doses will be administered in proportion to populations, so by the end of 2021, Southeast Asia and Africa will be the regions that will receive the most doses. This is followed by.... 2,80 million in the Americas and the Caribbean....Obtaining these doses will depend on fundraising and other factors. However, the Initiative's calculations suggest that all countries, rich or poor, should be able to guarantee the immunization of health workers, the elderly and vulnerable groups before the end of the year.

 

[camberiu]

 

[antipodean]

Alberto Fernández firmará en las próximas horas un acuerdo con Xi Jinping por 30 millones de dosis de la vacuna contra el COVID-19 de Sinopharm

El Ministerio de Salud y la empresa china negocian la letra chica de un contrato que al principio permitirá suplir una mínima parte de las vacunas rusas que debían llegar en febrero a Buenos Aires

www.infobae.com

Looks like Argentina may soon have a third contract in addition to Gamaleya and Astrazenaca with 1m doses that should arrive in FEB.

What do we know about Sinopharm?

Is it true that the government have actually abandoned further discussions with Pfizer so no more hope of a contract there?

Es un secreto de Estado que podría revelarse en las próximas horas: Alberto Fernández está a un paso de lograr un acuerdo con Xi Jinping por la provisión de 30 millones de dosis de la vacuna china contra el COVID-19. Es una noticia formidable para la Casa Rosada que ayer descartó un acuerdo comercial con la empresa farmacéutica Pfizer y aguardó sin resultado que el Kremlin confirmara cuando aterrizarán en Ezeiza las 20 millones de vacunas Sputnik V que prometió el Fondo Ruso de Inversión Directa.

Desde una perspectiva científica y burocrática todo ya ha sido resuelto. Los análisis técnicos están en la ANMAT, y Aerolíneas Argentinas tiene alistada una hoja de ruta para viajar sin demoras a Beijing. Cuando el vuelo charter finalmente aterrice en Buenos Aires, Ginés González García tiene previsto comunicar que se concedió la autorización para aplicar la vacuna de Sinopharm.

 

[dsp27]

Client Challenge

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[artisans]

The Lancet publicó datos sobre la vacuna Sputnik V: mostró efectividad de 91,6 % y no registró efectos adversos graves

The Lancet publicó datos sobre la vacuna rusa Sputnik V: mostró una efectividad de 91,6 % y no registró efectos adversos graves

La prestigiosa revista científica difundió finalmente información técnica de la fase III del desarrollo del Instituto Gamaleya contra el COVID-19, cuyas dosis son aplicadas en la Argentina y en otros países de América Latina

www.infobae.com

Alberto Fernández firmará en las próximas un acuerdo con Xi Jinping por 30 millones de dosis de la vacuna contra el COVID-19 de Sinopharm

Alberto Fernández firmará en las próximas horas un acuerdo con Xi Jinping por 30 millones de dosis de la vacuna contra el COVID-19 de Sinopharm

El Ministerio de Salud y la empresa china negocian la letra chica de un contrato que al principio permitirá suplir una mínima parte de las vacunas rusas que debían llegar en febrero a Buenos Aires

www.infobae.com

Argentina seeking agreement with Russia to produce Sputnik V vaccine

Argentina seeking agreement with Russia to produce Sputnik V vaccine

Newly appointed ambassador to Russia, Eduardo Zuain, says government is seeking a deal with Russia to manufacture Sputnik V vaccine in Argentina.

www.batimes.com.ar

 

[gracielle]

Client Challenge

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Full Text:

Sputnik V COVID-19 vaccine candidate appears safe and effective

Denis Logunov and colleagues1 report their interim results from a phase 3 trial of the Sputnik V COVID-19 vaccine in The Lancet. The trial results show a consistent strong protective effect across all participant age groups. Also known as Gam-COVID-Vac, the vaccine uses a heterologous...

www.thelancet.com

 

[gracielle]

Covid: Israel's vaccine rollout linked to infection fall

Less than 0.1% of vaccinated people caught coronavirus, and far fewer became ill.

www.bbc.com

Update: 2 February 2021

Palestinians give first COVID-19 vaccines after Israel shares supply

Palestinian Authority administered its first known coronavirus vaccinations on Tuesday after receiving thousands of doses from Israel, which launched its

english.alarabiya.net

 

[gracielle]

Alberto Fernández firmará en las próximas horas un acuerdo con Xi Jinping por 30 millones de dosis de la vacuna contra el COVID-19 de Sinopharm

El Ministerio de Salud y la empresa china negocian la letra chica de un contrato que al principio permitirá suplir una mínima parte de las vacunas rusas que debían llegar en febrero a Buenos Aires

www.infobae.com

....What do we know about Sinopharm?

Full Text:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30843-4/fulltext

Sinopharm Covid-19 Vaccine efficacy better than expected - Khmer Times

Is the Chinese vaccine safe? How long is the protection duration?

www.khmertimeskh.com

Pfizer or Sinopharm? COVID-19 'vaccine diplomacy' in Middle East

Pfizer or Sinopharm? The United States or China? In the Middle East and North Africa, COVID-19 vaccine orders are driven by diplomatic and ...

www.channelnewsasia.com

Coronavirus: How effective are the Chinese vaccines?

Some countries have already approved vaccines from China or are currently participating in trials. But how effective and safe are the vaccines?

www.dw.com