Covid Vaccination Argentina

gracielle

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Everyone needs to take their own decision, but personally I think I'll wait: as Gracielle posted on the previous page, these vaccines are the original ones developed for COVID, not the bivalent ones starting to be used in Europe now. ...
I agree...each of us must arrive at our own conclusions. The following 2 articles offer dissimilar views.
3 October 2022 by Stephani Desmond
In this Q&A, adapted from the October 3 episode of Public Health On Call, Stephanie Desmon speaks with virologist Andy Pekosz, PhD, a professor in Molecular Microbiology and Immunology, about what makes bivalent boosters different—and more effective. Pekosz discusses who should get the bivalent shot and when, whether it’s safe to get it at the same time as the flu shot, and more....

This article is protected by a paywall. I am posting 90% of it which, in my opinion, is relevant to this topic.
25 October 2022 by Robert Langreth
Bivalent booster shots from Moderna Inc. and Pfizer Inc. failed to raise levels of protective proteins called neutralizing antibodies against the dominant omicron strains any more than four doses of the original Covid vaccine, according to an early independent study on a small group of people. Researchers at Columbia University and the University of Michigan compared levels of neutralizing antibodies in blood samples from 21 people who got a fourth shot of the Moderna anf Pfizer bivalent boosters against antibody levels in 19 people who got four shots of the original vaccines.

Three to five weeks after a fourth shot, those people who received the new boosters aimed at BA.4 and BA.5 variants “had similar neutralizing antibody titers as those receiving a fourth monovalent mRNA vaccine,” the authors conclude in a manuscript posted on the preprint server bioRxiv.org. This held true for antibodies that protect against BA.4, BA.5 and older variants such as the original omicron strain, according to the study....The results don’t mean that getting a bivalent shot has no benefit, and it will need to be confirmed in much larger studies. However, they raise the question of whether the switch to a new version of the vaccine was necessary....

....In early October, Moderna researchers published data from the clinical trial of a different bivalent booster that is tailored to the original omicron strain. That study, in the New England Journal of Medicine, found that a fourth shot of that bivalent vaccine produced higher levels of antibodies compared to four shots of Moderna’s original vaccine. Moderna’s bivalent vaccine against the original omicron strain, called mRNA-1273.214, is not authorized in the U.S., but has been cleared for use in numerous countries including the UK and Canada. Nonetheless, scientists have harbored doubts about the benefit of switching up the shots’ composition. Before the US began rolling out updated boosters in September, John Moore, a professor of microbiology and immunology at Weill Cornell Medical College said the new vaccines would be “little or no better” than earlier formulations.
 

gracielle

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The article Gracielle quoted indicated the bivalent ones might arrive here in summer.
I am definitely not waiting for the ARG national Ministry of Health to order, pay and receive the Moderna or Pfizer bivalent vaccines!
As I posted on Oct. 14th....The combination of vaccines has worked well to keep me Covid-free. I have been inoculated with 2 doses of AstraZeneca, 1 with J&J/Janssen, the first booster with Pfizer and the 2nd booster with Moderna (in May 2022). I will be in the US in April, 2023.
If by then the studies show that the bivalent boosters are an improvement over the original ones, I will get inoculated there.
 
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gracielle

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Update: Yesterday (Sat) at 8:00am I called #147 to confirm that those over the age of 50 who qualify to receive the 5th shot (if the 4th shot was applied more than 120 days ago) may arrive at the vaccination centers w/o an appt as stated in the article.

Per the operator: "at this call center we have yet to be informed of that directive". He suggested I use the City website to schedule the appt online as many "turnos" are available for the week of Nov. 14-18 at the authorized vaccination centers which are open Mon-Fri from 8:00am-4:00pm.
https://www.buenosaires.gob.ar/coronavirus/vacunacion-covid-19
The system will accept as ID: DNI Ext (Foreign), Pasaporte (Foreign), Residencia Precaria (con foto)

I scheduled my "turno" for Monday, Nov 14. I received the confirmation email exactly 24 hrs later. If you decide to re-schedule, you must first cancel the original "turno" prior to the appointed date before the system allows you to schedule a new one.
I arrived this morning at Club San Lorenzo at 10:30am for the "turno" I had selected on Sat via the City website. This vaccination center was
well organized, the staff was very friendly and efficient. I was in and out in 25 minutes. This included the 15-min waiting period after the inoculation with Moderna.

This is what I was told when I inquired. "We don't know where Clarin, TN and Radio Mitre got the idea that people can show up without a "turno". Nevertheless we are not turning anybody away. The persons with a "turno" will have priority. The ones without will be inoculated as well but may experience a waiting time of about 15-20 extra minutes. For those, the best time to show up is before 10:30am".
 

gracielle

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16 Nov 2022 by Pablo Sigal
...."Please, let's use the vaccines! The request was made this Tuesday by the Director General of the Pan American Health Organization (PAHO), Carissa Etienne, when she gave an overview of the health situation in the region to journalists from all over the continent. Etienne said that the region is facing a triple threat: Covid, influenza and RSV (respiratory syncytial virus)....This virus, which causes bronchiolitis, cannot be prevented as there is no vaccine for it today. In several countries of the northern hemisphere it is causing full hospital capacities. The expert also recommended that the governments of the different countries should once again advise their populations to wear masks in the face of the appearance of new respiratory transmission infections. She said that the experience of the pandemic should be utilized to make use of this resource whenever needed....

....Jairo Méndez Rico, PAHO regional advisor for emerging viral diseases, referred specifically to the Covid situation and stressed that "there are no new variants", but rather lineages and sub-lineages of Omicron. In particular, he mentioned the BQ.1 sub lineage of the BA.5 subvariant, which has gained prominence especially in the USA and is gradually gaining influence in South America. He assured that there is no evidence that it is more aggressive. He added: "They are all Omicron". Finally, he assured that although the arrival of a new generation of vaccines adapted for Omicron will be welcome in view of the boosters that the populations will have to receive, the existing vaccines against Covid have never ceased to be effective against serious disease and death.
 

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Automatic Google Translation of entire article:
14 November 2022 by Romina Cansler
Vegetable vaccine against COVID: what is the situation of the trial that recruited more than 7,000 Argentines. Infobae spoke with Gonzalo Pérez Marc, the principal investigator at the Military Hospital....Today, more than a year after the first immunizations within the study, what happened to this project and why....
 

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18 November 2022 by Thomas Mulier/Bloomberg
Pfizer Inc. released more evidence that its new Covid vaccine boosts protective antibodies against dominant Omicron variants more than the original booster. Pfizer and its German vaccine partner BioNTech SE said Friday that the bivalent booster may provide better protection against the Omicron BA.4 and BA.5 sublineages. The results were similar to those of a study in people aged 55 years and older published earlier this month. The U.S. Food and Drug Administration authorized the emergency use of the bivalent booster for people over 5 years of age, and the European Commission authorized it for marketing in the European Union.
 

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Automatic Google Translation of entire article:
22 November 2022 by Madison Muller and Robert Langreth/Bloomberg
Covid-19: Vaccine boosters only offer short-term protection against omicron. Covid-19 booster shots from Moderna and the Pfizer-BioNTech partnership that fight the latest omicron variants provide some short-term protection against mild infections, but experts say it 's not yet clear whether the updated vaccines are better than previous versions in preventing hospitalization and serious illness....Among adults younger than 49 years, boosters were 43% effective in preventing minor illnesses compared to getting no vaccine at all. In people between the ages of 50 and 64, the comparative protection against symptomatic Covid was 28%, while the booster only provided 22% protection in adults 65 and older, according to the study....
 

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