COVID-19 vaccine development pipeline gears up

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7 December 2021
The government is preparing another flight to Moscow next week to bring the second shipment of vaccines, the date being evaluated at this time is January 14. It will bring the second dose of the 300 thousand vaccines that arrived on December 24.

Although everything indicated that the next trips would be to South Korea or India, where the Russian vaccine is produced for the Argentine market, the Government launched a travel plan to return to the Russian capital. The date that is evaluated is January 14 at 8:35 in the morning, to return to Buenos Aires on the 15th around midnight. But everything can change with the market for vaccines. In fact, the first trip also suffered modifications due to administrative issues that were resolved at the last minute....
 
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7 January 2021
Coronavirus: Sinovac vaccine shows 78% effectiveness in Brazil
SAN PABLO.- A coronavirus vaccine developed by Sinovac Biotech was 78% effective in late-phase clinical trials in Brazil, São Paulo state authorities said Thursday, in a step forward for the efforts of Chinese pharmaceutical companies to match the results of its western peers.

Brazil and Indonesia, which have the highest number of coronavirus cases in Latin America and Southeast Asia respectively, are preparing to start using Sinovac's CoronaVac vaccine this month. Sinovac also has supply agreements with Turkey, Chile, Singapore, Ukraine and Thailand....
 
7 January 2021
Interview:
"Nothing indicates that vaccines are not suitable for new strains of the coronavirus," says British virologist Daniel Bausch
The expert assures that at the moment the mutations are not so great. And he foresees that it will only return to a certain "normality" in 6 months.

The British Kent and South African variants of Covid-19 are rapidly advancing in 40 and 22 countries respectively. The definitive answer to these mutations will be in the cultures and in the laboratory studies, which have not been completed. So far "there is no evidence that forces to alter the composition of existing vaccines." But we will have to wait "at least 6 to 8 months to regain a certain normality", which will not be like before.

This is the diagnosis of Professor Daniel Bausch, British virologist, specialist in tropical medicine, director of the Rapid Support Team for British Public Health, researcher at the London School of Hygiene and Tropical Medicine and a long and respected track record of virus research in Sub-Saharan Africa, in Latin America and Asia on Ebola, Lassa, hantavirus and SARS coronavirus. One of the most respected and authoritative voices in the world to analyze Covid and its Kentish and South African variants...
 
7 January 2021
Vaccines against the coronavirus: The Government confirmed the arrival of the second round of Sputnik V, while negotiating with China and Brazil
In addition to announcing the arrival of new doses of the vaccine of Russian origin, the Government is making progress in the negotiations to finalize the purchase of one million Sinopharm vaccines, which would begin to arrive from China in the coming weeks. There are also open negotiations with Brazil to acquire the Coronavac vaccine, from the Chinese laboratory Sinovac and developed by the Butantan Institute....
....The minister added that at the end of March "a very important quantity of the vaccine manufactured here" will be added to these doses from Russia, in reference to the one developed by the pharmaceutical company AstraZeneca. He also gave an account of the negotiations for the Sinopharm vaccine: "Today we are negotiating with China one million doses for January," he detailed. In addition, he assured that "negotiations continue" with other suppliers and reiterated that "a new proposal was made to Pfizer to see if they accept."...
 
7 January 2021
A new vaccine against COVID-19 with nanoparticles that will not need refrigeration and will be a single dose is being developed at Stanford University, in the United States
. It has already been tested in mice and human trials will begin soon. It is especially aimed at developing countries that have logistical difficulties in distributing already approved vaccines....University researchers have said that this development was based on their experience in studies of vaccines against HIV, Ebola and pandemic influenza, which were in development before the coronavirus outbreak spread around the world.

Although SARS-CoV-2 is outside the laboratory's specific area of specialization, since the declaration of the pandemic, Stanford researchers have been developing a promising vaccine candidate against this virus, which already has important advances. “Our goal is to make a single-shot vaccine that does not require a cold chain for storage or transportation. If we get it right, it should also be cheap, ”said Peter S. Kim, who is a professor of biochemistry at Virginia and DK Ludwig. "The target population for our vaccine is low- and middle-income countries."....
 
7 January 2021
Russian vaccine vs Chinese vaccine: how they differ and what are their side effects
The Government confirmed the arrival of one million doses of the Sinopharm vaccine. The Fundacion Huesped had begun a phase three trial of the vaccine in September. How does it work....

In an exchange of letters, President Alberto Fernández wrote to Xi Jinping, the Chinese president, that "Argentina is prepared to strengthen cooperation with China in various sectors, including vaccines." Beijing responded positively and they will cooperate in the research, development and application of vaccines against SARS-CoV-2. In total, they hope to buy between 15 and 30 million doses of Sinopharm vaccines.

At the end of August, the Ministry of Health agreed with China to start a clinical trial of Sinopharm. In September, the infectious disease specialist Pedro Cahn, director of Fundacion Huesped, announced the beginning of Phase 3. Three thousand persons were enrolled in the study and it will last 12 months. The tests are financed by the Argentine laboratory Elea....
HOW THE SPUTNIK V AND SINOPHARM VACCINES ARE DIFFERENT....
 
7 January 2021
Vaccine Sputnik V: how long does it take to reach immunity against the covid after receiving the first dose
. The effect of the antidote in the body is not instantly. It requires a process which could have a delay between 14 days and a month. What will happen if the second inyeccion is postponed....
 
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