COVID-19 vaccine development pipeline gears up

[gracielle]

Coronavirus en la Argentina: Carla Vizzotti dijo que evalúan aplicar una sola dosis de la Sputnik V para "vacunar a más gente"

Coronavirus en la Argentina: Carla Vizzotti dijo que evalúan aplicar una sola dosis de la Sputnik V para "vacunar a más gente"

www.lanacion.com.ar

11 January 2021
Coronavirus in Argentina: Carla Vizotti said that they are evaluating applying a single dose of Sputnik V to "vaccinate more people".
The Secretary of Access to Health, Carla Vizotti, assured today that the government of Alberto Fernández is evaluating applying a single dose of the Russian vaccine Sputnik V against the coronavirus to accelerate the immunization process of the population. That way, the official said, they could have 20 million people inoculated in March...."In this context of a pandemic, it is very logical to think that more people can be vaccinated with the first dose and defer the second until the outbreak is already under control," Vizotti said in an interview with the newspaper Página 12....

 

[artisans]

Coronavirus en la Argentina: Carla Vizzotti dijo que evalúan aplicar una sola dosis de la Sputnik V para "vacunar a más gente"

Coronavirus en la Argentina: Carla Vizzotti dijo que evalúan aplicar una sola dosis de la Sputnik V para "vacunar a más gente"

www.lanacion.com.ar

11 January 2021
Coronavirus in Argentina: Carla Vizotti said that they are evaluating applying a single dose of Sputnik V to "vaccinate more people".
The Secretary of Access to Health, Carla Vizotti, assured today that the government of Alberto Fernández is evaluating applying a single dose of the Russian vaccine Sputnik V against the coronavirus to accelerate the immunization process of the population. That way, the official said, they could have 20 million people inoculated in March...."In this context of a pandemic, it is very logical to think that more people can be vaccinated with the first dose and defer the second until the outbreak is already under control," Vizotti said in an interview with the newspaper Página 12....

Music to the ears!!

 

[gracielle]

Avanza la vacuna contra el Covid de AstraZeneca y Oxford: a fines de marzo llegarían las dosis a la Argentina

Los componentes que se producen en el país se enviarían el próximo lunes a México para ser envasados. Los expertos plantean dudas por el plan del Gobierno de dar solo una dosis de la vacuna Sputnik V

www.clarin.com

11 January 2021
....The country would have at its disposal the new doses of the Russian Sputnik V vaccine that will arrive between January and February. They are expected to be from both the first and second doses. The 9 million doses of vaccines from the Covax fund would also arrive by March or April, the Pan American Health Organization told this newspaper.
....However, the Russian vaccine is the only one that is being applied for now in the country, since the contract with Pfizer is on hold. Sputnik vaccination began in December in health personnel. There are 300,000 doses of component 1. According to the latest update, carried out on Friday, at least a third (107,542) has already been applied.

 

[gracielle]

¿Una dosis en vez de dos? La escasez de vacunas y la segunda ola hacen repensar las estrategias

Las Fases III de los estudios de Pfizer y Moderna mostraron que una sola inyección parece proporcionar una fuerte protección, y EEUU y el Reino Unido ya se plantean retrasar la segunda aplicación para intentar inmunizar a más personas. Qué se sabe de la Sputnik V

www.infobae.com

11 January 2021
One dose instead of two? Vaccine shortages and second wave rethink strategies Phase III of the Pfizer and Moderna studies showed that a single injection appears to provide strong protection, and the US and UK are already considering delaying the second application to try to immunize more people. What is known about Sputnik V.

....Can the second dose of the COVID-19 vaccine be received later than initially recommended? Could half doses be given? And using a different vaccine between the first and second doses, is it just as effective? Governments around the world are now facing these questions in the face of an ongoing pandemic and with the emergence of apparently more contagious variants of the coronavirus.

With with limited vaccine supplies and hundreds of millions of people waiting to be immunized against SARS-CoV-2, the situation leaves experts grappling with the complicated debate about whether nations should vaccinate fewer people with the best. possible protection or inoculate twice as many people with a single dose, covering more population but with slightly less protection....

 

[gracielle]

UPDATE: 11 January 2021

Luego de negar la entrada, el régimen chino autorizó que la OMS ingrese al país para investigar sobre el origen del COVID-19

La llegada estaba programada para la semana pasada, pero fue cancelada en el último minuto porque el régimen de Xi Jinping puso trabas a la comisión argumentando que no había conseguido todas las autorizaciones necesarias. La pesquisa podría comprometer a Beijing por su presunto encubrimiento de...

www.infobae.com

The team of experts from the World Health Organization (WHO) - in charge of investigating the origin of the new coronavirus and which was due to arrive in China last week - will begin its mission on Thursday, the Chinese Ministry of Health announced on Monday.

It is a very delicate visit for China, interested in ruling out any responsibility in the epidemic that has caused more than 1.9 million deaths in the world...The mission is made up of ten scientists from Denmark, the United Kingdom, the Netherlands, Australia, Russia, Vietnam, Germany, the United States, Qatar and Japan, recognized in their different fields of expertise....

 

[gracielle]

Rusia inició los análisis clínicos de la “Sputnik Light”, una vacuna de una sola dosis

La Fase 1 de ensayos comenzó con 150 voluntarios para conocer la seguridad y protección inmunológica de la fórmula, un estudio que terminará a finales de 2021. La candidata está dirigida al mercado exterior

www.infobae.com

11 January 2021
Russia began clinical analysis of “Sputnik Light”, a single-dose vaccine Phase 1 trials began with 150 volunteers to learn about the safety and immunological protection of the formula, a study that will end in late 2021. The candidate is targeted to the foreign market...

As reported by the Gamaleya Center, 150 volunteers will participate in the first analyzes of "Sputnik Light" in three laboratories in Moscow and Saint Petersburg. The Russian Ministry of Health authorized the start of tests to determine the safety and immunological protection of the vaccine, a process that will last almost a year and will end at the end of 2021....

 

[Dougie]

I'm not a scientist, but to anyone here who is...does this seem like a good idea?

If they haven't done a trial on just one dose then they don't know if it will be effective or not, correct? If it doesn't work well then they will have wasted many doses it seems. I would think that you want to follow the exact protocol that they did during the trial. But, I have no idea how any of this works.

 

[gracielle]

I'm not a scientist, but to anyone here who is...does this seem like a good idea?

If they haven't done a trial on just one dose then they don't know if it will be effective or not, correct? If it doesn't work well then they will have wasted many doses it seems. I would think that you want to follow the exact protocol that they did during the trial. But, I have no idea how any of this works.

FDA says half-dosing Moderna COVID-19 vaccine ‘risks public health,’ lacks data

Following reports that the U.S. Food and Drug Administration was in talks with Moderna and Operation Warp Speed officials to consider halving vaccines’ dose volume to speed inoculations and extend supply, the federal watchdog late Monday dismissed the approach, calling it a “significant public...

www.foxnews.com

Studies to see if Moderna COVID-19 vaccine doses can be halved may take 2 months

Scientists at the National Institutes of Health and Moderna Inc (MRNA.O) may take about two months to determine whether doses of the company's COVID-19 vaccine can be halved to double the supply of the shots in the U.S., according to the agency.

www.reuters.com

Feds may cut Moderna vaccine doses in half so more people get shots, Warp Speed adviser says

Federal officials have said the U.S. will need to vaccinate roughly 80 percent of the population to achieve herd immunity against the coronavirus.

www.politico.com

 

[antipodean]

My only concern would be if I can be guaranteed a second dose (should it be necessary) when it falls due or otherwise be sure there is not a risk of a weaker long term prognosis should it be delayed (eg lost effectiveness)
The main reason for this concern is that the Russian vaccine is known for having production limitations and doubts surrounding it - the reason that Hungary and some other countries walked away from it.
Kicking the can down the road or adopting a false sense of security rarely ends up well.

 

[jeff1234]

[QUOTE = "antipodean, post: 400672, member: 67082"]
My only concern would be if I can be guaranteed a second dose (should it be necessary) when it falls due or otherwise be sure there is not a risk of a weaker long term prognosis should it be delayed (eg lost effectiveness)
The main reason for this concern is that the Russian vaccine is known for having production limitations and doubts surrounding it - the reason that Hungary and some other countries walked away from it.
Kicking the can down the road or adopting a false sense of security rarely ends up well.
[/ QUOTE]

Didn't they already skip the third phase of the Sputnik trials?