COVID-19 vaccine development pipeline gears up

antipodean

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News from the neighbors regarding the sinovac vaccine - apparently only 50.4% effective but at least appearing to reduce the severity of the illness in the other 50%.

There has been concern and criticism that Chinese vaccine trials are not subject to the same scrutiny and levels of transparency as its Western counterparts.”
 

dsp27

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News from the neighbors regarding the sinovac vaccine - apparently only 50.4% effective but at least appearing to reduce the severity of the illness in the other 50%.

There has been concern and criticism that Chinese vaccine trials are not subject to the same scrutiny and levels of transparency as its Western counterparts.”
The trials, were directly supervised by the Butantan institute a very reputable research center in Brazil. I also know of someone in Brazil following the program. Brazil has many problems but one thing they do well -- vaccination. Excellent programs due to decades of experience dealing with infectious diseases. Won't be surprised is they finish vaccinating their entire population before Argentina in the end.
 

gracielle

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13 January 2021
Chinese manufacturer Sinovac claimed its coronavirus vaccine has high efficacy after Brazil said it is 50.38%.
The company's president, Yin Weidong, said that trials had found it to be 100% effective in preventing serious cases and that the company was expanding its production capacity to meet domestic and foreign demand....
...."These data (from Brazil) show that the vaccines have good efficacy and safety in all phase 3 clinical trials," Yin said. And he added: "We have accelerated the increase in production capacity."....
....This was the company's first reaction after its Brazilian partner Butantan published data on Tuesday showing an efficiency rate of 50.38%, just barely exceeding the threshold set by most regulators and well below the recommended 70%. by the World Health Organization....
 

antipodean

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Maybe I have missed something but the question I have is if it only “prevents” 50% of recipients from being infected by COVID, when the other 50% contract it (albeit a “mild form”), are they still passing it on to others who have not been vaccinated? Do they people who have been vaccinated still practice the same degree of caution in public and social settings or do they relax their behavior? Do they unvaccinated people the vaccinated person infects also have a “mild form” of COVID or risk serious complications regardless?

Even in China vaccinations have reached 1-2% of the population, if they had COVID levels like Brazil and Argentina it would appear do little to actually slow the spread and usher in a “return to normality” in the short-mid term should those with the vaccine who contract the virus still be able to pass it on. Preventing serious cases and preventing infection seems like two different subjects?

El estudio no permite afirmar que esta vacuna erradicará la enfermedad, pero sí que será capaz de controlar la pandemia mediante la elevada reducción de las hospitalizaciones”, afirmó el director de investigaciones médicas del Instituto Butantan, Ricardo Palacios, en rueda de prensa.
 
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gracielle

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13 January 2021
Russian vaccine: the next 4.7 million doses would arrive in "quotas" and from India and Korea.
....Diario Clarín knew - based on information a few days ago from a government source - that, once the 300,000 doses of the second component of the Russian Sputnik V vaccine land on Saturday, another 4,700,000 vials will arrive from India or South Korea. What was not known until now was whether they would all fly together or in different lots. Now it is known that the doses will come in installments.

How many doses will Russia send per week and beginning when? It is not known. It is the intention that at least one flight - again, in addition to the one that will arrive this Saturday - occurs before the end of January. "In this we go to day to day, talking to Russia and putting together the travel scheme," explained the source, for whom the pace of the campaign does not justify the declining horizon announced by President Alberto Fernández at the beginning of December.

In other words, by February there should be enough doses to vaccinate 10 million people, "with the possibility of adding another 5 million in the summer months," said the person consulted.


Regardless of whether that will be possible, it is advisable to stop in the context, which only requires tying up some ends. A couple of months ago, it was circulating through the ministerial corridors that there were difficulties in communication with Russia to agree from the most basic to the most complex of the logistics "vaccines". And then, a week ago, an official source showed its ample predisposition by stating "we are going to look for them wherever (the Russians) tell us."

Argentina is not exempt from the world equation that combines a very high demand for vaccines with severe limitations in production. The government can push for the deadlines stipulated in the contract signed with its Asian counterpart to be met, but the handling on
logistics (from dates to how many doses will be shipped) seems to be in Russia....

....According to the consulted Health source, "Russia approved giving it to people over 60, but did not send the corresponding documentation" to the ANMAT. It is easy to imagine a bitter taste, a product of that delay....
 
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antipodean

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An interesting vaccination strategy underway in Indonesia - younger people who are more active outside the house (and thus more likely to come in contact with and spread the virus) are the first to receive it in order to get the economy and society back up to speed faster and cut down on new infections sooner.
 

gracielle

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