I've said this before...I've seen loads of closures, but every day a new shop opens. Rents on buildings that line those main shopping arteries are highly inflated because it used to be 'the area' to shop. So, businesses either close up or move to a more affordable barrio where they can operate without such high overhead.
In the last month there've been seven new business openings in a one-block radius of my place (cafes and restaurants, an indie book/art shop). I think it'd be disingenuous to say it's the government alone, or solely the rise of online shopping. Business turnover is a thing that is constantly happening, especially in large cities as trends change, as other neighborhoods become more dynamic...attracting storefronts away from the old 'main drags,' which here would be Santa Fe and Cabildo perhaps?
Hope isn't gone. I still buy everything in brick and mortar stores and never use mercado libre or Rappi. I just prefer human interaction and actually being able to see a product before I pay for it. I also hate waiting at home through what feels like a 10 hour delivery window in the name of 'convenience' when I could just hop out, run over to a shop and buy it in less time. I can't be tied down to my apartment for that nonsense. It's brutal waiting on deliveries here. Personal preference. The best thing to do is make sure to support those small businesses you hold dear, as much as you can while ya have em near. That can be said for a lot of things. The impermanence this life, is the only certainty we have.