My opinion is that with the kind of budgets you are talking about you would be wise to be discreet and I don't think San Telmo is not the place for someone with your kind of money/spending.
I think you would be better off in Palmero Viejo (Soho) or Las Canitas. I think you'd like it there if you like San Telmo & it's safer.
In fact, there was a lovely boutique hotel near San Telmo not too long ago who have in fact MOVED to Palermo.
http://www.casa-monserrat.com/ is now Baucis Palermo.
I think you would be better off in Palmero Viejo (Soho) or Las Canitas. I think you'd like it there if you like San Telmo & it's safer.
In fact, there was a lovely boutique hotel near San Telmo not too long ago who have in fact MOVED to Palermo.
http://www.casa-monserrat.com/ is now Baucis Palermo.