Thanks so much for the Craigslist tip - and to everyone in general on the feedback. Like I said, I've worked in public safety in my home state; I understand murders and assaults happen and can happen anywhere. And of course I also know that if there are street corners monopolized by people selling sex or drugs - well, obviously you want to avoid those. Also having been raised on the east coast I DO feel safer in a city if there's people around at night -- figuring if people AREN'T around, there's a reason for that!
I do have another lead on a place smack in the middle of Recoleta and I'm wondering if maybe it might be wisest to take that place for a couple months while I get a feel for the city and its various areas.