chris said:Museums in San Telmo?
Ahem...
Museo Historico Nacional (Parque Lezama facing Defensa)
Museo de Arte Moderno (Av San Juan 350)
Museo Penitenciario (Humberto Primo 378 -- an old convent later turned into a women's prison)
Zanjon de Granados (Defensa 755 -- awesome architectural site underneath the modern-day San Telmo)
Museo del Titere (Piedras 905 -- a puppet museum, but still)
Museo del Traje (Chile 832 -- basically a fashion museum)
Concerning safety, I lived there for six months and never had problems. It does get a little shady west of Chacabuco, but nothing to be terrified about if you watch yourself.