COVID-19 vaccine development pipeline gears up

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3 November 2020...
Nelson Castro raised serious objections about the Russian vaccine
The journalist and physician explained various shortcomings that Sputnik V showed in phase 1 and phase 2, which the government wants to buy.
The most important news yesterday was the possibility that the Argentine government would buy 25 million doses of the Russian Sputnik V vaccine between December of this year and January 2021, if it completes phase 3. The event generated various reactions and repercussions, between those who were happy and those who doubted. That is why the TN program "Solo Una Vuelta Más" invited Nelson Castro to bring clarity. In addition to being a journalist he is a physician and has been studying the subject extensively.

“There is an article in The Lancet, one of the medical bibles, that found the main objections. In the first place, it is a vaccine that is not known how it completed phase 1 and phase 2. There is no clear information on how the level of neutralizing antibodies was, or how those antibodies were compared with people who had been infected," he explained. Castro also warned that technically there are "important flaws" that do not allow evaluating the immunogenicity strength of the vaccine, and that according to the article, there is a very good possibility of generating antibodies during the first four weeks, but it cannot be verified what may happen passed that time.

“In the article it is said that two doses will be necessary every two years, but it is striking because nobody knows how long the immunogenicity of the vaccine will last, because until now only two or three months have passed. Saying that it will provide immunity for two years is a fallacy," said the neurologist and journalist from TN.

The third critical point, for Castro, is that what is known about phase 1 and phase 2 is that it was tested on 72 people, but it is not known when it was applied to each one, so there is no information about how long the antibody response was assessed. Another objection is that phase 3 is still missing, the most important part since it is when testing is done with a larger quantity of volunteers.

Finally, Castro explained that a member of the Russian Institute Gamaleya said that the vaccine is being made without following the legal parameters established by the Russian Ethics Commission, and after that denouncement they threw him out." It can become a great vaccine, but so far there is no reason to say that they are going to buy 25 million, because for now this vaccine only offers doubts," he closed.
 
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3 November 2020
Their technical director speaks. Russian vaccine in Argentina: the mysterious San Isidro laboratory that will act as a “bridge” between the Russians and the Government....

 
Did they mentions the the Russia is charing Argentina over 20 bucks per dose? The EU negotiated to buy the AstraZeneca vaccine when available for under 5 euros per dose.
We are talking of half a BILLION dollars for an unproven vaccine.
 
Corruption, graft and kickback schemes are the hallmark of the Peronist party. It would be very naive to think that there isn’t anything shady behind these dealings regarding the mystery Covid vaccine. So to show good faith and dispel any malicious rumors why not have the President and the VP be the first ones to be injected with this magic elixir. This could be done in a press conference type setting. This would show the rest of the country that they have full confidence on the product.
 
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Did they mentions the the Russia is charing Argentina over 20 bucks per dose?

El costo de la Sputnik V es de 19,90 dólares.


Here is an interesting point
La secretaria de Acceso a la Salud recordó que la ley de vacunas establece que "debe ser gratuita y obligatoria". Pero advirtió: "Entendemos que esta situación es muy particular y que necesitamos construir confianza. Preferimos trabajar brindando información y que la población adhiera a las vacunas. La primera instancia no va a ser de obligatoriedad".
 
Corruption, graft and kickback schemes are the hallmark of the Peronist party. It would be very naive to think that there isn’t anything shady behind these dealings regarding the mystery Covid vaccine. So to show good faith and dispel any malicious rumors why not have the President and the VP be the first ones to be injected with this magic elixir. This could be done in a press conference type setting. This would show the rest of the country that they have full confidence on the product.

They will inject them with a saline solution jaja
 
Maybe they realize their only hope of winning next years election is to deploy a big smokescreen to get people excited again. Desperate popularists will pay any price for propaganda, even $20 a dose for what could effectively be a placebo.

By removing legal recourse against the producers and making it “optional” to receive the vaccine, the scene is already set for the government to escape its own responsibilities should shit hit the fan in terms of longer term side effects.

On the other hand, this kind of vaccine did work against Ebola and should not be discounted before it can be disproven. Likewise it should not be consumed before it can be proven either.
 
4 November 2020
Why the coronavirus vaccine should not be mandatory....
4 November 2020
Why the coronavirus vaccine should be mandatory

 
2 November 2020
It was officially confirmed
Argentina will buy 25 million doses of the Russian vaccine Sputnik V against the coronavirus

The first 10 million doses will arrive in December and the rest in January. It was announced this Monday by President Alberto Fernández. "By December we could start the vaccination," he said, and acknowledged that he himself will be immunized with Sputnik V against the new coronavirus....

There was an unpleasant projection in this article: "Its differential characteristic is the use of two different adenoviruses to generate the antibody response....That allows researchers to expect up to 70-80% effectiveness, against 30-50% of others in the race." I was rather hoping for 100%.
 
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