What a odd question. You need to be as safe as possible. You are in as much danger as anyone living in a large city!!!!!!!!!!!! Don't assume because your female, pretty, str8, gay, tall, or short you have any special powers for not being robbed. Be aware of your surroundings, take proactive measures to avoid being a victim and count yourself as lucky.
Watch out for taxi drivers who will rob you and men who will drug you. It doesn't matter what part of the city your in, its all the same. My friends get mugged in Puerto Madero and the Recoletta. Don't stop to talk to strangers at midnight and keep moving. Just be smart all the time! But above all have a great time and enjoy the City!