"Coronavirus: Oxford vaccine triggers immune response"

[FrankPintor]

AstraZeneca Covid-19 vaccine study put on hold due to suspected adverse reaction in participant in the U.K.

AstraZeneca's Covid-19 vaccine study has been put on hold due to a suspected adverse reaction in participant in the U.K.

www.statnews.com

This is the second pause, the sky hasn't fallen in (just) yet.

 

[gracielle]

This is the second pause, the sky hasn't fallen in (just) yet.

Please provide the data re: when the first pause took place and the reason(s) for the halt.

 

[FrankPintor]

Please provide the data re: when the first pause took place and the reason(s) for the halt.

It's been mentioned in a few places, in the Guardian's live coverage for example, here's another link: https://www.oxfordstudent.com/2020/...cine-trials-paused-after-participant-illness/

"Despite this being the second pause since trials began in April..."

 

[gracielle]

AstraZeneca Pauses Vaccine Trial for Safety Review (Published 2020)

The company halted late-stage trials of its coronavirus vaccine because of a serious suspected adverse reaction in a participant.

www.nytimes.com

....A person familiar with the situation, who spoke on the condition of anonymity, said that the participant who experienced the suspected adverse reaction had been enrolled in a Phase 2/3 trial based in the United Kingdom. The individual also said that a volunteer in the U.K. trial had received a diagnosis of transverse myelitis, an inflammatory syndrome that affects the spinal cord and is often sparked by viral infections. However, the timing of this diagnosis, and whether it was directly linked to AstraZeneca’s vaccine, is still unknown.

Transverse myelitis can result from a number of causes that set off the body’s inflammatory responses, including viral infections, said Dr. Gabriella Garcia, a neurologist at Yale New Haven Hospital. But, she added, the condition is often treatable with steroids.

AstraZeneca declined to comment on the location of the participant and did not confirm the diagnosis of transverse myelitis. “The event is being investigated by an independent committee, and it is too early to conclude the specific diagnosis,” the company said....

 

[gracielle]

Oxford and AstraZeneca resume coronavirus vaccine trial

The vaccine being developed by Oxford and AstraZeneca is widely perceived to be one of the strongest contenders among the dozens of coronavirus vaccines in various stages of testing around the world.

www.pbs.org

 

[gracielle]

September 30, 2020 6:40pm UPDATED 14 hours ago

Exclusive: FDA widens U.S. safety inquiry into AstraZeneca coronavirus vaccine - sources

The U.S. Food and Drug Administration has broadened its investigation of a serious illness in AstraZeneca Plc's COVID-19 vaccine study and will look at data from earlier trials of similar vaccines developed by the same scientists, three sources familiar with the details...

www.reuters.com

....AstraZeneca’s large, late-stage U.S. trial has remained on hold since Sept. 6....

 

[Redpossum]

Less than 50% of Americans would take Covid-19 vaccine, even if they were paid $100 – poll

Mounting skepticism around a Covid-19 vaccine in the US continues, with less than half of respondents saying they’d take one even if they were offered $100, according to a new poll.

www.rt.com

Personally, I suffer from mounting skepticism about polls. And with a sample size of "over 1000" people, this one has a sizable margin of error. But still, I found it amusing to learn that many of my countrymen are skeptical of any vaccine. Note that this poll didn't say which vaccine.

 

[gracielle]

Vaccine hopes rise as Oxford jab prompts immune response among old as well as young adults

One of the world's leading COVID-19 experimental vaccines produces an immune response in both young and old adults, raising hopes of a path out of the gloom and economic destruction wrought by the novel coronavirus.

www.reuters.com

 

[Redpossum]

never mind...

 

[gracielle]

AstraZeneca COVID-19 vaccine trial Brazil volunteer dies, trial to continue

Brazilian health authority Anvisa said on Wednesday that a volunteer in a clinical trial of the COVID-19 vaccine developed by AstraZeneca <AZN.L> and Oxford University had died but added that the trial would continue.

www.reuters.com

UPDATE: 22 Oct 2020 at 7:30am....Canal Trece, interview of Dr. Nelson Castro who confirmed that "the Brazilian volunteer who died of COVID-19 was a 28 year-old physician who had been given a placebo".

AstraZeneca vaccine trial would have stopped if deceased volunteer part of active arm - source

The Brazilian trial of the COVID-19 vaccine candidate by the University of Oxford and AstraZeneca would have been suspended if the volunteer who died had been part of the active arm, a source familiar with the situation said on Wednesday.

www.reuters.com